AI or a multiplayer match vs other people, but there's no single-player campaign. Unfortunately, the story basically ends there. Sounds like an interesting potential plot, right?- Gray-and-Grey Morality, possible Eldritch Abominations, who knows what else. All while the humans, who they initially thought would be easy targets, dragged them down into a Hopeless War. and watching in dismay as those buoys wink out, one by one. The remnants of a Vasari colony, now surviving as nomadic Planet Looters, have fled to this corner of the galaxy, leaving warning buoys behind them. Every ship sent to investigate this menace has disappeared, except for one ship which returned with its crew driven mad. And there's the Vasari, Scary Dogmatic Aliens who once ruled a huge interstellar empire, but whose worlds have been gradually swallowed by.
There's the Advent, transhumans who were exiled by the traders' ancestors many years ago for tampering with Psychic Powers, Crystal Spires and Togas and Frickin' Laser Beams, and are now back for Revenge. There's the Trader Emergency Coalition, a semi-cohesive organization of human worlds who have banded together to try to defend their worlds from aggression, using Kinetic Weapons, heavy armor and Macross Missile Massacres.